DAY 1 – Saturday, 16 November | |
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9:30 – 10:00 | Registration |
10:00 – 10:10 | Welcome: Wayne Tilley (Dame Roma Mitchell Cancer Research Laboratories, University of Adelaide, Adelaide), Sheel Nuna (Queensland University of Technology, Brisbane) |
10:10 – 10:20 | Opening: Caroline McMillen, Chief Scientist South Australia, Adelaide |
10:20 – 10:50 | Keynote Address: Vinod Scaria (CSIR Institute of Genomics and Integrative Biology, New Delhi) “Personal genomes to precision medicine – Experiences from India” |
10:55 – 11:15 | Break (Coffee) |
11:15 – 12:40 | Session 1: Developmental processes in disease: new roles for old friends
Chairperson: Frank Gannon (QIMR Berghofer Medical Research Institute, Brisbane)
- Kum Kum Khanna (QIMR Berghofer Medical Research Institute, Brisbane) “DNA damage response in normal tissue homeostasis”
- Natasha Harvey (Centre for Cancer Biology, Adelaide) “Understanding the genetic and developmental basis of human lymphatic vascular disease”
- Raman Sharma (University of Adelaide, Adelaide) “THOC2 variation implicates mRNA export in neurodevelopmental disorders: 45 years of perseverance pays off”
- Anuranjan Anand (Jawaharal Nehru Centre for Advanced Scientific Research, Bengaluru) “Stem cells in breast cancer initiation and progression”
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12:40 – 1:30 | Lunch |
1:30 – 3:00 | Session 2: Bridging basic science and public health outcomes
Chairperson: Klaus-Martin Schulte (Australian National University, Canberra)
- Anthony Cunningham (Westmead Institute for Medical Research, Sydney) “Striking improvements in vaccine efficacy in the ageing through new immunologic strategies”
- Kumarasamy Thangaraj (CSIR – Centre for Cellular and Molecular Biology, Hyderabad) “Population genomics and public health”
- Meru Sheel (Australian National University, Canberra) “Operational research in public health emergencies for prevention and control of infectious diseases outbreaks”
- Sutapa B. Neogi (Public Health Foundation of India, New Delhi) “Walking the fine line between science and culture: its impact on health”
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3:00 – 3:20 | Break (Coffee) |
3:20 – 4:50 | Session 3: The disease micro-environment
Chairperson: Rik Thompson (Queensland University of Technology, Brisbane)
- Severine Navarro (QIMR Berghofer Medical Research Institute, Brisbane) “Hookworms and gut microbiome: focus on new therapeutic avenues”
- Bhupinder Pal (Olivia Newton-John Cancer Research Institute, Melbourne) “Using ScRNAseq to identify molecular events that shape tumour heterogeneity and microenvironment”
- Michael Samuel (Centre for Cancer Biology, Adelaide) “Probing biomechanical and biochemical inter-relationships in breast cancer progression”
- Steve Birrell (University of Adelaide, Adelaide) “Breast density – the hidden danger”
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4:50 – 5:00 | Break |
5:00 – 6:05 | Session 4: Epigenetics vs genetic drivers of disease
Chairperson: Jyotsna Batra (Queensland University of Technology, Brisbane)
- Shama Prasada (Manipal Academy of Higher Education, Manipal) )“Understanding the regulation and biological function of miRNA clusters in cervical cancer”
- Luke Selth (Flinders University / University of Adelaide, Adelaide) “Elucidating the androgen receptor cistrome in prostate cancer”
- Sudha Rao (University of Canberra, Canberra) “Epigenetic driven reinvigoration: Progress from mechanism to therapeutics and liquid biopsies in immune-oncology”
Keynote Talk: Mohan Rao (Consultant Transplant Surgeon, Adelaide) “The history and impact of renal transplantation in India” |
6:10 – 6:40 | Special Presentation: Mohan Rao (Consultant Transplant Surgeon, Adelaide) “The history and impact of renal transplantation in India”
Chairperson: Wayne Tilley
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6:40 – 6:50 | Welcome to Country |
7:15 | Welcome Dinner |
DAY 2 – Sunday, 17 November | |
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9:00 – 10:35 | Session 5: Stem cells: mechanisms and models of disease
Chairperson: Elizabeth Williams (Queensland University of Technology, Brisbane)
- Mark Nottle (University of Adelaide, Adelaide) “Embryonic stem cells. A tale of mice and men as well as pigs”
- Sharmila Bapat (National Centre for Cell Science, Pune) “Cancer stem cells and phenotypic plasticity in metastases”
- Cedric Bardy (South Australian Health & Medical Research Institute, Adelaide) “Modeling human brain disorders in vitro”
- Annapoorni Rangarajan (Indian Institute of Science, Bengaluru) “Stem cells in breast cancer initiation and progression”
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10:35 – 11:10 | Break (Coffee) |
11:10 – 12:45 | Session 6: Omics and disease
Chairperson: John Bruning (University of Adelaide, Adelaide)
- Lisa Butler (University of Adelaide / South Australian Health & Medical Research Institute, Adelaide) “Lipidomics identifies clinically targetable biomarkers for prostate cancer”
- Daniel Kolarich (Institute for Glycomics, Griffith University, Brisbane) “Glycomics and glycoproteomics – deciphering the glyco-language of diseases”
- Mark Corbett (University of Adelaide, Adelaide) “Genomic approaches for discovery of non-coding variants in neurodevelopmental disorders”
- Ashwani Kumar (ICMR-Vector Control Research Centre, Puducherry) “Proteogenomic and transcriptomic approaches for accurate assembly and annotation of genomes”
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12:45 – 1:45 | Lunch |
1:45 – 3:25 | Session 7: New insights into disease mechanisms and novel therapeutic targets
Chairperson: Wendy Ingman (Basil Hetzel Institute/University of Adelaide, Adelaide)
- Sharad Kumar (Centre for Cancer Biology, Adelaide) “Caspase-2 dependent suppression of aneuploidy and tumourigenesis”
- Liz Caldon (Garvan Institute for Medical Research, Sydney) “BRCA1 mutation stabilises cyclin E1 in breast cancer to create a therapeutically targetable subset”
- David Waugh (Queensland University of Technology, Brisbane) “Re-education of tumor-associated macrophages in advanced prostate cancer”
- Harsha Gowda (QIMR Berghofer Medical Research Institute, Brisbane) ”Novel avenues for therapeutic intervention based on proteogenomic landscape of esophageal squamous cell carcinoma”
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3:25 – 3:50 | Break (Coffee) |
3:50 – 5:25 | Session 8: Immune response and immunotherapy
Chairperson: Michael Brown (Royal Adelaide Hospital, Adelaide)
- Shaun McColl (University of Adelaide, Adelaide) “The atypical chemokine receptor ACKR4 restrains anti-tumour immunity through regulation of CCL21”
- Simon Phipps (QIMR Berghofer Medical Research Institute, Brisbane) “Novel approaches for the treatment of viral bronchiolitis and prevention of later asthma”
- Nic Waddell (QIMR Berghofer Medical Research Institute, Brisbane) “Whole genome and RNAseq sequencing of cancers to predict response to immunotherapy”
- Rajiv Khanna (QIMR Berghofer Medical Research Institute, Brisbane) “Harnessing the cellular immunity to fight cancers and infectious complications”
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5:25 – 5:30 | Short Break |
5:30 – 6:00 | Special Presentation – Guest speaker: Professor Tom Calma AO, Chancellor, University of Canberra, Canberra. “Major challenges and successes in Indigenous health with a focus on prevention strategies and the importance of social and cultural determinants”
Chairperson: Sheel Nuna
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6:10 – 6:30 | Buses depart from AHMS for conference dinner |
7:00 | Conference Dinner |
DAY 3 – Monday, 18 November | |
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9:00 – 10:35 | Session 9: Better models of human disease
Chairperson: Judith Clements (Queensland University of Technology, Brisbane)
- Maria Kavallaris (Children’s Cancer Institute, University of New South Wales, Sydney) “3D bioprinting tumours: Applications in drug screening and cancer biology”
- Kaylene Simpson (Peter MacCallum Cancer Centre, Melbourne) “Using high throughput cellular phenotyping to screen for novel disease targets”
- Renea Taylor (Monash University, Melbourne) “Using patient-derived xenografts to unveil prostate cancer phenotypes”
- Theresa Hickey (University of Adelaide, Adelaide) “What’s best for breast”
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10:35 – 11:00 | Break (Coffee) |
11:00 – 12:30 | Session 10: Towards realising precision medicine
Chairperson: Wayne Tilley (University of Adelaide, Adelaide)
- Shom Goel (Peter MacCallum Cancer Centre, Melbourne) “CDK4/6 inhibition in cancer – more than cell cycle arrest.”
- Chamindie Punyadeera (Queensland University of Technology, Brisbane) “Liquid biopsy for detection of patients likely to develop metastasis in HNC and NSCLC”
- Melissa Davis (Walter and Eliza Hall Institute, Melbourne) “Molecular phenotypes and precision medicine: In silico sorting, subtyping and single patient analysis”
- Prashant Kumar (Institute for Bioinformatics, Bengaluru) )“Patient derived circulating tumor cell cluster phenotype allows monitoring response to treatment and predicts survival”
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12:30 – 1:20 | Lunch |
1:20 – 3:20 | Session 11: Realising precision medicine
Chairperson: Frank Gannon (QIMR Berghofer Medical Research Institute, Brisbane)
- Philippa Middleton (South Australian Health & Medical Research Institute, Adelaide) “Can we reduce preterm birth through precision medicine?”
- Deborah White (University of Adelaide / South Australian Health & Medical Research Institute, Adelaide) “A systematic approach to understanding the factors that impact response of ALL patients to current therapies”
- Rebecca Robker (University of Adelaide, Adelaide) “Childhood obesity starts with egg and sperm”
- Susan Woods (South Australian Health & Medical Research Institute, Adelaide) “Patient derived organoids to guide personalised treatment for bowel cancer“
- Elgene Lim (Garvan Institute of Medical Research, Sydney) “Window (trials) to precision medicine”
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3:20 – 3:30 | Short Break |
3:30 – 4:00 | Keynote Speaker: Alex Brown, Theme Leader, Aboriginal Health Equity, South Australian Health & Medical Research Institute, Adelaide “Overcoming inequity among indigenous Australians” |
4:00 – 4:15 | Meeting Close – Wayne Tilley and Sheel Nuna |